National Cancer Genetics MDT
The National Cancer Genetics MDT (UKCGG National CGM) is a collaboration between the CanGene-CanVar Programme and the UK Cancer Genetics Group (UKCGG), which aims to create a regular national forum to discuss complex cancer genetics cases, improve patient management and expand clinical knowledge.
For patient confidentiality and clinical governance, meeting attendees will be required to register for the meeting in advance and are required to work within the NHS in the area of cancer genetics.
National Cancer Genetics MDT Objectives:​
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Creation of a national multidisciplinary professional network and regular forum to discuss and advise on complex cancer genetics cases.
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Improve outcomes and consistency of care for patients by facilitating multidisciplinary discussion.
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Identify areas in which national guidelines are required or need updating.
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Improve training and education in clinical cancer genetics.
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Facilitate relevant publications in peer-reviewed journals based on cases discussed, best practice guidelines and the value of a national forum for clinicians and patients.
If you are a member of the British Society for Genetic Medicine (BSGM) and are interested in becoming part of the UKCGG, please click here for more information.
Please see our resources below for an up-to-date list of meeting summaries, educational tools, references and web-based links.
Register to attend the next MDT
You must register in advance for this meeting.
For patient confidentiality and clinical governance, meeting attendees will be required to register for the meeting in advance and are required to work within the NHS in the area of cancer genetics - please ensure that you register with your full name and NHS or academic email
Next meeting: November 21st 2024, 12:30pm - 1:45pm.
The Newcastle clinical genetics team will be leading, with a theme of "Constitutional Mismatch Repair Deficiency (CMMRD)".
Please register via the following link:
https://us06web.zoom.us/meeting/register/tJ0vce-oqTsrGdFaSQ6RNDU0MYGkzPT8KGWQ
After registering, you will receive a confirmation email containing information about joining the meeting.
National Cancer Genetics MDT Format
​Bi-monthly 60-75 minute MDT via Microsoft Teams (with the possibility to increase this to monthly)​
Current time slot: 12:30-13:45, 3rd Thursday of the month, starting 15th October (to review future dates and alter if required)
Ground rules for the meeting will be circulated to all attendees
MDT to alternate between:
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Expert topic - Short presentation by an invited expert and then discussion of 3-4 cases relevant to that specific topic
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Mixed cases - Approx. 6 cases to include a mixture of cases where a clinical decision is required and "known" cases highlighting a specific learning point
Cases to be submitted in advance of the meeting using a set slide format clearly stating clinical questions or learning points
Cases which involve variant classification should be discussed in Can-VIG
Cases which involve significant ethical issues/debates should be discussed in GenETHICS
There will be nominated session Chair (Consultant in Cancer Genetics/Senior GC) which can be rotated through different centres
CPD accreditation (RCP) if possible
The Chair will select the cases for discussion and run the meeting with the help of an additional person to minute discussions and agreed actions
At least one representative from each centre should attend
Resources
Created by Helen Hanson, Anju Kulkani, Fiona Lalloo and Marc Tischkowitz on behalf of UKCGG Council and CanGene-CanVar.
A summary document of the UKCGG National Cancer Genetics MDT meeting on 19th September 2024 Topic: A themed session on "Discussion of familial ovarian cancer NICE guidelines"
A summary document of the UKCGG National Cancer Genetics MDT meeting on 20th September 2023 Topic: A themed session on ATM Heterozygotes.
UKCGG National CGM Presentation
(Exponent scoring system for variant classification)
Meeting date: 11 February 2021
Presentation slides from Dr Alice Garrett, Clinical Research Fellow, Institute of Cancer Research
UKCGG Cancer Genetics MDT July 2024 (Variants outside the test directory)
Meeting date: 18 July 2024
A summary document of the UKCGG National Cancer Genetics MDT meeting on 18th July 2024 Topic: A themed session on "To report or not report: Variants outside the test directory e.g. ATM c.2251-10T>G"
A summary document of the UKCGG National Cancer Genetics MDT meeting on 16th May 2024 Topic: Mixed cases.
UKCGG National CGM Presentation (Andrew George-The potential benefit of MMR, MSI and TMB as SoC in the RMH Diagnostic pathway considering the introduction of the NHS National Genomic Test Directory)
Meeting date: 17 November 2022
UKCGG Cancer Genetics MDT May 2021 Summary (Mixed Cases)
Last updated: 28 May 2021
A summary document of the UKCGG National Cancer Genetics MDT meeting on 20th May 2021. Topic: A mixed case session, discussion of multiple cancer types and management.
UKCGG National CGM Summary
(Clinical considerations of variant classification and reclassification)
Meeting date: 11 February 2021
A summary document of the UKCGG National Cancer Genetics MDT meeting on 11th of February 2021. Topic: clinical considerations of variant classification and reclassification.
UKCGG National CGM Presentation
(BRCA reclassification cases)
Meeting date: 11 February 2021
A summary document of the UKCGG National Cancer Genetics MDT on the 17th of December 2020. Topic: Mixed Cases.
UKCGG National CGM Summary
(Li-Fraumeni Syndrome and heritable TP53-related cancer (hTP53rc) syndrome)
Meeting date: 15 October 2020
A summary document of the first UKCGG National Cancer Genetics MDT on the15th of October 2020. Topic: Li-Fraumeni Syndrome and heritable TP53-related cancer (hTP53rc) syndrome.